Asia Pac IPO & Placement Research, China biotech, Aequitas Research

Ke Yan, CFA, FRM

Asia Pac IPO & Placement Research, China biotech

IPOs and Placements coverage across Asia Pacific

Aequitas Research

We cover all listing across the Asia Pacific along with follow-up placements. As of Dec 2020, our team had covered 539 IPOs with a hit rate of 73.5% and 685 placements with a hit rate of 66.8%.

We combine fundamental bottom-up views with our proprietary quantitative framework to provide a holistic coverage across new listings and placements. Our coverage includes pre-IPO notes before the deal is launched, follow-up analysis once the deal is live and post-listing trading analysis as well.

Equity Capital Markets

<p>Broncus Holding is a leading interventional pulmonology company in China and globally. The company launched book building to raise up to USD 215m via a Hong Kong listing.</p><p></p><p>In our previous note, we discussed that the company's core product, InterVapor, is a minimally invasive surgery that uses heated water vapor to treat the chronic obstructive pulmonary disease (COPD). In addition to the COPD indication, the company plans to further develop the product for the treatment of lung cancer. Another core product, RF-II uses radio frequency to treat lung cancer. Besides InterVapor and RF-II, the company also has a commercialized lung navigation system which has a leading market share in China. However, we believe the market for the lung navigation system is still in the early stage of development in China and hence the small market size.  We think the company has a strong pre-IPO investor line-up with backing from the founder of VenusMedtech and its management team is experienced. We also provided our thoughts on valuation of Broncus.</p><p></p><p>In this note, we provide an update for the book building. We will run the deal through our ECM framework and provide an update on the deal.</p>

Broncus Holding is a leading interventional pulmonology company in China and globally. The company launched book building to raise up to USD 215m via a Hong Kong listing.In our previous note, we discussed that the company's core product, InterVapor, is a minimally invasive surgery that uses heated water vapor to treat the chronic obstructive pulmonary disease (COPD). In addition to the COPD indication, the company plans to further develop the product for the treatment of lung cancer. Another core product, RF-II uses radio frequency to treat lung cancer. Besides InterVapor and RF-II, the company also has a commercialized lung navigation system which has a leading market share in China. However, we believe the market for the lung navigation system is still in the early stage of development in China and hence the small market size.  We think the company has a strong pre-IPO investor line-up with backing from the founder of VenusMedtech and its management team is experienced. We also provided our thoughts on valuation of Broncus.In this note, we provide an update for the book building. We will run the deal through our ECM framework and provide an update on the deal.

Broncus (堃博医疗) IPO: Long Term Faith Needed

IPOs and Catalysts/Events, Global Equity Research Ltd

Arun George

IPOs and Catalysts/Events

Uncompromised, Independent, Conflict-Free Research

Global Equity Research Ltd

Global Equity Research was started in 2017 by a group of experienced research professionals. It was founded on a passionate belief in the importance and the need for uncompromised, independent, conflict-free research. We aim to provide differentiated and actionable primary and bottom up fundamental research.

<p><a href="https://www.smartkarma.com/entities/broncus-holding-corporation" target="_blank" data-smartkarma-citation="entities:33315:1" rel="noopener">Broncus (BRC HK)</a> is a medical device company focused on the development of interventional pulmonology products. Broncus has 17 products and major product candidates under various development stages. The core products are <em>InterVapor</em>, the world’s first and only thermal vapour energy ablation system to treat lung diseases and <em>RF-II</em>, which is the only radiofrequency ablation system that specifically targets lung cancer.</p><p>Broncus has a credible management team with a commendable commercialisation track record and blue-chip backers. Pre-IPO investors include Qiming Venture Capital, DiNovA Capital, Lake Bleu Capital, FountainVest and <a href="https://www.smartkarma.com/entities/intuitive-surgical-inc" target="_blank" data-smartkarma-citation="entities:15853:1" rel="noopener">Intuitive Surgical (ISRG US)</a>. Broncus is pre-marketing an HKEx IPO to raise $300 million, according to press reports. </p><p>Broncus currently generates revenue primarily from navigation systems (LungPoint Plus, LungPro, LungPoint and planners) where it ranks second in China with a market share of 37.5% measured by sales revenue for the years ended 2018, 2019 and 2020, according to Frost &amp; Sullivan. However, the market is relatively small as the market size of interventional pulmonology diagnostic consumables in China reached just $26.3 million in 2020, according to Frost &amp; Sullivan. </p><div class="content-highlight"><p>Broncus’s core products aim for a large addressable market by targeting the pulmonary disease treatment market. The core products' differentiation in terms of technology and target indications increases the probability of success. Overall, we believe that Broncus’ product portfolio is attractive. </p></div>

Broncus (BRC HK) is a medical device company focused on the development of interventional pulmonology products. Broncus has 17 products and major product candidates under various development stages. The core products are InterVapor, the world’s first and only thermal vapour energy ablation system to treat lung diseases and RF-II, which is the only radiofrequency ablation system that specifically targets lung cancer.Broncus has a credible management team with a commendable commercialisation track record and blue-chip backers. Pre-IPO investors include Qiming Venture Capital, DiNovA Capital, Lake Bleu Capital, FountainVest and Intuitive Surgical (ISRG US). Broncus is pre-marketing an HKEx IPO to raise $300 million, according to press reports. Broncus currently generates revenue primarily from navigation systems (LungPoint Plus, LungPro, LungPoint and planners) where it ranks second in China with a market share of 37.5% measured by sales revenue for the years ended 2018, 2019 and 2020, according to Frost &amp; Sullivan. However, the market is relatively small as the market size of interventional pulmonology diagnostic consumables in China reached just $26.3 million in 2020, according to Frost &amp; Sullivan. Broncus’s core products aim for a large addressable market by targeting the pulmonary disease treatment market. The core products' differentiation in terms of technology and target indications increases the probability of success. Overall, we believe that Broncus’ product portfolio is attractive. 

Shanghai NewMed Medical / Equity Capital Markets

<p>Shanghai NewMed, a China-based heart valve medical device company, plans to raise up to USD 200m via a Hong Kong listing.</p><p>The company's core TAVR (transcatheter aortic valve replacement) product Prizvalve is a few years behind its competitors, despite its unique balloon expandable design. The selling point for the company is that in the international market such design is better than the self-expandable design which is mainstream in China. On the other hand, the company is leading the TMVR (transcatheter mitral valve replacement) development which is potentially a bigger market than the TAVR. </p><p>The company has quality institutional investors alongside individual investors, as well as an experienced management team. We think investors should follow the IPO.</p>

Shanghai NewMed, a China-based heart valve medical device company, plans to raise up to USD 200m via a Hong Kong listing.The company's core TAVR (transcatheter aortic valve replacement) product Prizvalve is a few years behind its competitors, despite its unique balloon expandable design. The selling point for the company is that in the international market such design is better than the self-expandable design which is mainstream in China. On the other hand, the company is leading the TMVR (transcatheter mitral valve replacement) development which is potentially a bigger market than the TAVR. The company has quality institutional investors alongside individual investors, as well as an experienced management team. We think investors should follow the IPO.

NewMed (纽脉医疗) Pre-IPO: Uphill Battle for TAVR but Leads the TMVR

Jenscare Scientific / Equity Capital Markets

<p>Jenscare, a China based structural heart disease focused medical device company, plans to raise up to USD 300m via a Hong Kong listing.</p><p>There have been many aortic heart valve replacement (TAVR) companies listed in Hong Kong but we think Jenscare has a differentiated portfolio in the area of heart valve replacement. Its TTVR product for the tricuspid valve will be leader the market for a few years and its TAVR product has a different indication for aortic regurgitation vs the aortic stenosis from other TAVR players. </p><p>With quality pre-IPO investors, experienced management team and differentiated portfolio, we think investors should follow the IPO.</p>

Jenscare, a China based structural heart disease focused medical device company, plans to raise up to USD 300m via a Hong Kong listing.There have been many aortic heart valve replacement (TAVR) companies listed in Hong Kong but we think Jenscare has a differentiated portfolio in the area of heart valve replacement. Its TTVR product for the tricuspid valve will be leader the market for a few years and its TAVR product has a different indication for aortic regurgitation vs the aortic stenosis from other TAVR players. With quality pre-IPO investors, experienced management team and differentiated portfolio, we think investors should follow the IPO.

Jenscare (宁波健世科技) Pre-IPO: Differentiated Heart Valve Portfolio

Shanghai HeartCare Medical Technology / Equity Capital Markets

<div><p><a href="https://www.smartkarma.com/entities/shanghai-heartcare-medical-technology-corporation-limited" target="_blank" data-smartkarma-citation="entities:32192:1" rel="noopener">Shanghai HeartCare Medical Technology (6609 HK)</a> is a China-based neuro-interventional medical device manufacturer with a product portfolio that spans the treatment and prevention of ischemic stroke to the treatment of haemorrhagic stroke. HeartCare’s product portfolio consists of a total of 23 commercialised products and product candidates, including four ischemic stroke treatment devices with NMPA approval.</p></div><div><p>HeartCare has launched an HKEx IPO to raise net proceeds of HK$980.6 million ($126 million) at the mid-point of the IPO price range of HK$160.00-171.00 per share. Ten cornerstone investors will subscribe for $66 million worth of the offer shares (46.96% of the offer shares at the mid-point). Pricing will be finalised on 13 August and the shares will list on 20 August.</p></div><div><p>In <a href="https://www.smartkarma.com/insights/shanghai-heartcare-medical-ipo-initiation-surviving-strokes" target="_blank" data-smartkarma-citation="insights:50331" rel="noopener">Shanghai HeartCare Medical IPO Initiation: Surviving Strokes</a>, we opined that HeartCare only started to generate revenue in 1Q20 through the commercialisation of two products (SupSelek and ExtraFlex). Captor thrombectomy device, a core product, was commercialised in December 2020 and Fullblock balloon guiding catheter was commercialised in April 2021. HeartCare aims to commercialise nine currently late-stage product candidates in 2021 and ten currently earlier-stage product candidates between 2022 and 2025. With a strong near-term commercialisation pipeline, HeartCare has shifted from a concept to a revenue-generating stock. We concluded that HeartCare’s product portfolio is attractive.  </p></div><div><div>
<p>HeartCare is braving the moribund IPO market for Chinese stocks by seeking to raise a lower amount than the original target of a $300 million raise. Despite the sell-off on Chinese names, <a href="https://www.smartkarma.com/entities/zylox-tonbridge-medical-technology-co-ltd" target="_blank" data-smartkarma-citation="entities:32974:1" rel="noopener">Zylox-Tonbridge Medical Technology (2190 HK)</a>, a peer, is trading 9% above its IPO price (listed 5 July 2021), suggesting that sentiment on the Chinese medical devices sector remains positive.  </p>
<div class="content-highlight"><p>Our base-case DCF valuation is HK$186.51 per share, which is a 13% upside to the mid-point of the IPO price range of HK$160.00-171.00 per share. Consequently, we would participate in the IPO. </p></div>
</div></div>

Shanghai HeartCare Medical Technology (6609 HK) is a China-based neuro-interventional medical device manufacturer with a product portfolio that spans the treatment and prevention of ischemic stroke to the treatment of haemorrhagic stroke. HeartCare’s product portfolio consists of a total of 23 commercialised products and product candidates, including four ischemic stroke treatment devices with NMPA approval.HeartCare has launched an HKEx IPO to raise net proceeds of HK$980.6 million ($126 million) at the mid-point of the IPO price range of HK$160.00-171.00 per share. Ten cornerstone investors will subscribe for $66 million worth of the offer shares (46.96% of the offer shares at the mid-point). Pricing will be finalised on 13 August and the shares will list on 20 August.In Shanghai HeartCare Medical IPO Initiation: Surviving Strokes, we opined that HeartCare only started to generate revenue in 1Q20 through the commercialisation of two products (SupSelek and ExtraFlex). Captor thrombectomy device, a core product, was commercialised in December 2020 and Fullblock balloon guiding catheter was commercialised in April 2021. HeartCare aims to commercialise nine currently late-stage product candidates in 2021 and ten currently earlier-stage product candidates between 2022 and 2025. With a strong near-term commercialisation pipeline, HeartCare has shifted from a concept to a revenue-generating stock. We concluded that HeartCare’s product portfolio is attractive.  
HeartCare is braving the moribund IPO market for Chinese stocks by seeking to raise a lower amount than the original target of a $300 million raise. Despite the sell-off on Chinese names, Zylox-Tonbridge Medical Technology (2190 HK), a peer, is trading 9% above its IPO price (listed 5 July 2021), suggesting that sentiment on the Chinese medical devices sector remains positive.  
Our base-case DCF valuation is HK$186.51 per share, which is a 13% upside to the mid-point of the IPO price range of HK$160.00-171.00 per share. Consequently, we would participate in the IPO. 


Shanghai HeartCare Medical IPO: Valuation Insights

China

Venus MedTech (HangZhou) Inc. develops and sells cardiovascular devices. The Company offers products including aorta, compression loading and conveying systems, and pulmonary artery. Venus MedTech (HangZhou) markets its products throughout China.

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Venus MedTech (2500 HK)

Broncus (堃博医疗) IPO: Long Term Faith Needed

We provide an update for the book building of Broncus. The company has an interesting product portfolio but the sales ramp-up will be slow.

Ke Yan, CFA, FRM

Broncus IPO: Every Breath They Take

Broncus is pre-marketing an HKEx IPO to raise $300m. The core products' differentiation in terms of technology and target indications increases the...

Arun George

NewMed (纽脉医疗) Pre-IPO: Uphill Battle for TAVR but Leads the TMVR

NewMed plans to raise at least USD 200m via a Hong Kong listing. We take a look at its Prizvalve, replacement valve for the aortic valve, and Mi...

Ke Yan, CFA, FRM

Jenscare (宁波健世科技) Pre-IPO: Differentiated Heart Valve Portfolio

Jenscare has a differentiated heart valve portfolio with leadership in the tricuspid heart valve replacement segment. We think the company is...

Ke Yan, CFA, FRM

Shanghai HeartCare Medical IPO: Valuation Insights

Our base-case DCF valuation is HK$186.51 per share, which is a 13% upside to the mid-point of the IPO price range of HK$160.00-171.00 per share.

Arun George

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