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Quoin Pharmaceuticals  / Equity Bottom-Up

<ul><li>Between cash on hand and a recent arrangement for an equity line of credit for up to $8M, management believes that through its measures, it has extended its cash to maintain activities into late 2025.</li><li>This is expected to enable Quoin to continue moving QRX003 ahead through NS clinical trials and recent FDA clearance to recruit subjects 14 and older also allows Quoin to broaden the pool of people eligible to participate in the studies and thereby facilitate recruitment efforts.</li><li>Expanding the number of participants to an aggregate of 50 NS subjects also is expected to contribute to a more robust database to present for potential regulatory approval.</li></ul>

Between cash on hand and a recent arrangement for an equity line of credit for up to $8M, management believes that through its measures, it has extended its cash to maintain activities into late 2025.This is expected to enable Quoin to continue moving QRX003 ahead through NS clinical trials and recent FDA clearance to recruit subjects 14 and older also allows Quoin to broaden the pool of people eligible to participate in the studies and thereby facilitate recruitment efforts.Expanding the number of participants to an aggregate of 50 NS subjects also is expected to contribute to a more robust database to present for potential regulatory approval.

QNRX: Protocol Modifications Potentially Accelerate, Expand QRX003 Approvals

Israel

Clal Biotechnology Industries Ltd., invests in companies within the biological sector.

CollPlant Holdings Ltd. produces and distributes pharmaceutical products. The Company offers wound care, orthopedics, and tissue repair medicines. CollPlant Holdings conducts its business in the United States.

BioLineRx Ltd. is a clinical-stage biopharmaceutical company, which includes indentifying, in-licensing, and developing therapeutic candidates. Its in-licenses novel compounds, primarily from academic institutions and biotech companies based in Israel, and develops them through pre-clinical and clinical stages, and then partners with pharmaceutical companies clinical development and commercialization. The company was founded in April 2003 and is headquartered in Modi'in, Israel.

BioLineRx Ltd. is a biopharmaceutical development company. The Company develops clinical-stage therapeutic pharmaceutical drugs.

RedHill Biopharma is a specialty biopharmaceutical company primarily focused on the development and commercialization of late clinical-stage, proprietary drugs for the treatment of gastrointestinal diseases. RedHill's pipeline includes several drug candidates in advanced clinical development stages, including three Phase III-stage programs. The company promotes GI products in the U.S.

Allium Medical Solutions Ltd develops and produces medical equipment. The Company manufactures and markets minimally invasive products. Allium Medical Solutions serves customers worldwide.

ReWalk Robotics Ltd. produces a wearable robotic exoskeleton that provides powered hip and knee motion to enable individuals with Spinal Cord Injury (SCI) to stand upright and walk. ReWalk is available throughout the United States.

Sisram Medical Ltd manufactures medical equipment. The Company produces epilators, vascular therapy devices, pigmented variable treatment equipment, minimally invasive beauty equipment, and other equipment. Sisram Medical markets its products to medical beauty institutions worldwide.

Teva Pharmaceutical Industries Limited operates as a pharmaceutical company. The Company develops, manufactures, and markets generic and branded human pharmaceuticals, as well as active pharmaceutical ingredients. Teva Pharmaceutical Industries serves customers worldwide.

Bellicum Pharmaceuticals, Inc. operates as a biopharmaceutical company. The Company focuses on discovering and developing novel cellular immunotherapies for cancer, tumors, and blood diseases. Bellicum Pharmaceuticals serves patients in the United States.

Navidea Biopharmaceuticals Inc. is a biopharmaceutical company. The Company is focused on the development and commercialization of precision radiopharmaceutical diagnostics for diseases such as cancer.

Aravive, Inc. operates as a biotechnology company. The Company develops therapeutic proteins for the treatment of metabolic diseases and endocrine disorders. Aravive serves patients in the United States.

Invitae Corp. engages in the provision of genetic information into mainstream medical practice. It offer tests for disorders in cardiovascular, hereditary cancer, neurology, pediatrics, and other rare diseases. The company was founded by Randal W. Scott and Sean E. George on January 13, 2010 and is headquartered in San Francisco, CA.

Bionomics Limited operates as a biotechnology company, which specializes in the genetics field.  The Company, which is affiliated with a number of research institutions, seeks to develop a variety of genomic, genetic, molecular and cell biology techniques, which they believe will help demonstrate the onset and progression of diseases like epilepsy and breast cancer.

Salarius Pharmaceuticals Inc is a clinical-stage oncology company. The Company specializes in targeting the epigenetic causes of cancers and developing treatments for patients. Salarius Pharmaceuticals serves patients and customers in the State of Texas.

Bioxyne  Limited operates as a biotechnology company.  The Company specializes in the research, development and commercialization of diseases related to chronic obstructive pulmonary disease(COPD).

Trevena, Inc. develops pharmaceutical products. The Company offers discovery and development of agents targeting G-protein coupled receptors and therapies and drugs that treat acute heart failure, acute chronic pain, and depression. Trevena serves customers throughout the United States.

Sorrento Therapeutics, Inc. is a biopharmaceutical company. The Company researches human therapeutic antibodies for the treatment of cancer, inflammation, metabolic, and infectious diseases.

DorsaVi Ltd. develops and sells wireless sensor movement monitoring systems. The Company's technology is used by the to monitor workplace and sports related injury and pain.

Quoin Pharmaceuticals Ltd. operates as a specialty pharmaceutical company. The Company focuses on developing and commercializing therapeutic products that treat rare and orphan diseases. Quoin Pharmaceuticals serves customers worldwide.

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Quoin Pharmaceuticals (QNRX US)

QNRX: Protocol Modifications Potentially Accelerate, Expand QRX003 Approvals

Between cash on hand and a recent arrangement for an equity line of credit for up to $8M, management believes that through its measures, it has...

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