HK/China Healthcare Analyst (ex-Fosun Pharma)

Xinyao (Criss) Wang

Equity Capital Markets

Brii Biosciences / Equity Capital Markets

On April 8, 2021, <a href="https://www.smartkarma.com/entities/brii-biosciences" target="_blank" data-smartkarma-citation="entities:33014:1" rel="noopener">Brii Biosciences (1621985D US) </a>submitted its listing application to the main board of the Hong Kong Stock Exchange. Since June 2018, the Company has raised several rounds of funding with approximately US$414 million in total. In March of this year, Brii completed a US$155 million Series C financing with a post-financing valuation of US$1.455 billion. The founding investors include Boyu, 6 Dimensions, ARCH, Sequoia China, Yunfeng and BluePool, which are all well-known healthcare and biotech funds. Compared with the financing of tumor immunity and cell therapy projects, it is less common for large-scale financing in the field of anti-infection. So what makes the Company so special that it attracts so many star investors? This insight mainly analyzed the key product candidates and related concerns.

On April 8, 2021, Brii Biosciences (1621985D US) submitted its listing application to the main board of the Hong Kong Stock Exchange. Since June 2018, the Company has raised several rounds of funding with approximately US$414 million in total. In March of this year, Brii completed a US$155 million Series C financing with a post-financing valuation of US$1.455 billion. The founding investors include Boyu, 6 Dimensions, ARCH, Sequoia China, Yunfeng and BluePool, which are all well-known healthcare and biotech funds. Compared with the financing of tumor immunity and cell therapy projects, it is less common for large-scale financing in the field of anti-infection. So what makes the Company so special that it attracts so many star investors? This insight mainly analyzed the key product candidates and related concerns.

Pre-IPO Brii Biosciences - Insights on Pipeline and Related Concerns

Asia Pac IPO & Placement Research, China biotech, Aequitas Research

Ke Yan, CFA, FRM

Asia Pac IPO & Placement Research, China biotech

IPOs and Placements coverage across Asia Pacific

Aequitas Research

We cover all listing across the Asia Pacific along with follow-up placements. As of Dec 2020, our team had covered 539 IPOs with a hit rate of 73.5% and 685 placements with a hit rate of 66.8%.

We combine fundamental bottom-up views with our proprietary quantitative framework to provide a holistic coverage across new listings and placements. Our coverage includes pre-IPO notes before the deal is launched, follow-up analysis once the deal is live and post-listing trading analysis as well.

Brii Biosciences is a leading biotech company with focus on infectious disease. The company is looking to raise up to USD 400 million via a Hong Kong listing. We think Brii Biosciences is an interesting company with a potential to provide breakthrough therapy for HBV in China which will have a huge demand if the efficacy can be demonstrated, though the path of clinical trial is a bit complicated and lengthy. There is no effective therapeutic option for HBV at the moment and China's HBV patients accounted for one third of the HBV population in the world.  The company uses the siRNA technology that silences the protein synthesis for the HBV and hence reduces the antigents and presence of the virus in human bodies. RNA related technology was studied for more than 20 year and only gained attraction in terms of regulatory approval in recent years. With the early reading from the company and its licensing partners, we think the drug candidate BRII-179 and BRII-835 are promising. The company also has a strong management team and investor backing.

Brii Biosciences is a leading biotech company with focus on infectious disease. The company is looking to raise up to USD 400 million via a Hong Kong listing. We think Brii Biosciences is an interesting company with a potential to provide breakthrough therapy for HBV in China which will have a huge demand if the efficacy can be demonstrated, though the path of clinical trial is a bit complicated and lengthy. There is no effective therapeutic option for HBV at the moment and China's HBV patients accounted for one third of the HBV population in the world.  The company uses the siRNA technology that silences the protein synthesis for the HBV and hence reduces the antigents and presence of the virus in human bodies. RNA related technology was studied for more than 20 year and only gained attraction in terms of regulatory approval in recent years. With the early reading from the company and its licensing partners, we think the drug candidate BRII-179 and BRII-835 are promising. The company also has a strong management team and investor backing.

Brii Biosciences (腾盛博药) Pre-IPO: A Hopeful Tackle on HBV

China

Brii Biosciences operates as a biotechnology company. The Company discovers and develops therapeutics and medicines for the treatment of diseases. Brii Biosciences serves customers in the United States and China.

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Brii Biosciences (2137 HK)

Brii Biosciences (腾盛博药) Pre-IPO: A Hopeful Tackle on HBV

The company uses the siRNA technology that silences the protein synthesis for the HBV. RNA was studied for more than 20 year and only gained...

Ke Yan, CFA, FRM

Price Gauge

52-week Range

Market Cap (USDm)

P/E

Dividend (Yield)

Pre-IPO Brii Biosciences - Insights on Pipeline and Related Concerns

This insight mainly analyzed the core product candidates of Brii Biosciences in the pipeline (HBV, COVID-19 products and others), the competitive...

Xinyao (Criss) Wang

Brii Biosciences (腾盛博药) Pre-IPO: A Hopeful Tackle on HBV

The company uses the siRNA technology that silences the protein synthesis for the HBV. RNA was studied for more than 20 year and only gained...

Ke Yan, CFA, FRM