Covering IPOs, Healthcare and Technology Stocks

Andrei Zakharov

Algosun Global

Equity Bottom-Up

<p style="text-align: justify;">Previous week EU finally approved new contract with the German biotech company CureVac to purchase 225 million doses of COVID-19 vaccine and option to buy additional 180 million doses next year. CureVac plans to initiate global Phase 2b/3 clinical trials as soon as possible and is going to expand its manufacturing capacities to 300 million doses in 2021 and 600 million doses in 2022. New integrated European vaccine manufacturing network will be built in collaboration with several partners. We believe, that one of them is American EV and clean energy company Tesla, working with CureVac on vaccine RNA printer (version 3 is under development). We see further upside for CureVac shares and expect positive Phase 2a and Phase 2b/3 data of its vaccine candidate CVnCoV together with 90%+ efficacy and opportunity to sell ~100 million doses of COVID-19 vaccine for emergency use in the European Union this year.  </p>

Previous week EU finally approved new contract with the German biotech company CureVac to purchase 225 million doses of COVID-19 vaccine and option to buy additional 180 million doses next year. CureVac plans to initiate global Phase 2b/3 clinical trials as soon as possible and is going to expand its manufacturing capacities to 300 million doses in 2021 and 600 million doses in 2022. New integrated European vaccine manufacturing network will be built in collaboration with several partners. We believe, that one of them is American EV and clean energy company Tesla, working with CureVac on vaccine RNA printer (version 3 is under development). We see further upside for CureVac shares and expect positive Phase 2a and Phase 2b/3 data of its vaccine candidate CVnCoV together with 90%+ efficacy and opportunity to sell ~100 million doses of COVID-19 vaccine for emergency use in the European Union this year.  

CureVac Stock May Surge Another 20-30% Under New Bull-Case Scenario

Head of Research, IPOs & Placements, Aequitas Research

Sumeet Singh

Head of Research, IPOs & Placements

IPOs and Placements coverage across Asia Pacific

Aequitas Research

We cover all listing across the Asia Pacific along with follow-up placements. As of Dec 2020, our team had covered 539 IPOs with a hit rate of 73.5% and 685 placements with a hit rate of 66.8%.

We combine fundamental bottom-up views with our proprietary quantitative framework to provide a holistic coverage across new listings and placements. Our coverage includes pre-IPO notes before the deal is launched, follow-up analysis once the deal is live and post-listing trading analysis as well.

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<p><a href="https://www.smartkarma.com/entities/japan-airlines-co-ltd" target="_blank" data-smartkarma-citation="entities:1184:1" rel="noopener">Japan Airlines (9201 JP)</a> plans to raise around US$1.4bn in order to shore up its balance sheet and aid its longer term transformation.</p>
<p> I have covered the background of the deal in my earlier write-up, <a href="https://www.smartkarma.com/insights/japan-airlines-placement-given-the-uncertain-outlook-might-need-further-correction" target="_blank" rel="noopener">Japan Airlines Placement - Given the Uncertain Outlook, Might Need Further Correction</a>.</p>
</div><div><div id="annotable-executive_summary-2">In this insight, I'll talk about the updates since then.</div></div>


Japan Airlines (9201 JP) plans to raise around US$1.4bn in order to shore up its balance sheet and aid its longer term transformation.
 I have covered the background of the deal in my earlier write-up, Japan Airlines Placement - Given the Uncertain Outlook, Might Need Further Correction.
In this insight, I'll talk about the updates since then.

Japan Airlines Placement - Tricky Tricky, Needs to Correct

<p>Moderna may announce its first interim results of the late-stage trial of its COVID-19 vaccine mRNA-1273 as soon as this month. Pfizer and BioNTech confirmed its mRNA-based vaccine candidate against SARS-CoV-2 has already achieved success in first interim analysis from Phase 3 study. With 90%+ efficacy and study enrolled 43,538 participants Pfizer and BioNTech believe that a vaccine may effectively prevent COVID-19. BioNTech used mRNA-based approach and its vaccine candidate BNT162b2 consists of messenger RNA, that provides instructions for human cell to make immunogen, which activates the body’s immune response.</p><p style="text-align: justify;">Therefore, we see that unproven mRNA approach shows first promising results and this platform technology may also target solid tumors and many forms of cancer. Looks like leading mRNA-based vaccine producers (Moderna, Pfizer/BioNTech, CureVac) are going to win the race leaving behind adenovirus-based COVID-19 vaccine producers (J&amp;J, AstraZeneca, CanSino Biologics). Shares of BioNTech rose 19% in November while shares of Moderna and CureVac jumped 30% and 43% respectively this month. We believe that positive data from Moderna’s late stage study may drive stocks of mRNA-based vaccine producers to new highs.   </p>

Moderna may announce its first interim results of the late-stage trial of its COVID-19 vaccine mRNA-1273 as soon as this month. Pfizer and BioNTech confirmed its mRNA-based vaccine candidate against SARS-CoV-2 has already achieved success in first interim analysis from Phase 3 study. With 90%+ efficacy and study enrolled 43,538 participants Pfizer and BioNTech believe that a vaccine may effectively prevent COVID-19. BioNTech used mRNA-based approach and its vaccine candidate BNT162b2 consists of messenger RNA, that provides instructions for human cell to make immunogen, which activates the body’s immune response.Therefore, we see that unproven mRNA approach shows first promising results and this platform technology may also target solid tumors and many forms of cancer. Looks like leading mRNA-based vaccine producers (Moderna, Pfizer/BioNTech, CureVac) are going to win the race leaving behind adenovirus-based COVID-19 vaccine producers (J&amp;J, AstraZeneca, CanSino Biologics). Shares of BioNTech rose 19% in November while shares of Moderna and CureVac jumped 30% and 43% respectively this month. We believe that positive data from Moderna’s late stage study may drive stocks of mRNA-based vaccine producers to new highs.   

Success of Moderna’s COVID-19 Vaccine May Give a Boost to Stocks of Messenger RNA Companies

Asian Insight Provider - Actionable ideas, CrossASEAN Research

Henry Soediarko

Asian Insight Provider - Actionable ideas

CrossASEAN Research

At CrossASEAN Research we strive to produce unbiased and differentiated on the ground insights on companies across South East Asia. Our Research is produced for the most part after face to face meetings and conversations with company management to dig deep into the long term vision and strategy of the companies we cover. We seek to deliver investable and actionable themes on sectors and markets across SE Asia, often in collaboration with other Insight Providers across the region, pooling the vast experience of the analysts within the Smartkarma Ecosystem. We also offer bespoke work and tailor made trips for our clients. 

Insights across South East Asia

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<p>Less than a year since the news hit that the Chinese outbreak spread to the world, <a href="https://www.smartkarma.com/entities/pfizer-inc" target="_blank" data-smartkarma-citation="entities:1131:1" rel="noopener">Pfizer Inc (PFE US)</a> has announced its vaccine with more than <strong>90%</strong> effective in preventing Covid-19 among those without evidence of prior infection. Similar to <a href="https://www.smartkarma.com/insights/china-outbreak-theme-winners-and-losers" target="_blank" data-smartkarma-citation="insights:35971" rel="noopener">China Outbreak Theme: Winners and Losers</a> , this insight will discuss the potential winners and losers from the announcement of the vaccine. </p><p>Travel-related names such as airlines, airport operators, tour operators, the duty-free operators are the clear beneficiaries of this news while auto dealership will also benefit from the potential lower unemployment later on. </p><p>Instant noodle makers, pc makers that benefit from the work-from-home rush, as well as glove makers will no longer enjoy the same growth rate in 1H, and in the case of the glove makers, both ASP and volumes may see a decline. </p>

Less than a year since the news hit that the Chinese outbreak spread to the world, Pfizer Inc (PFE US) has announced its vaccine with more than 90% effective in preventing Covid-19 among those without evidence of prior infection. Similar to China Outbreak Theme: Winners and Losers , this insight will discuss the potential winners and losers from the announcement of the vaccine. Travel-related names such as airlines, airport operators, tour operators, the duty-free operators are the clear beneficiaries of this news while auto dealership will also benefit from the potential lower unemployment later on. Instant noodle makers, pc makers that benefit from the work-from-home rush, as well as glove makers will no longer enjoy the same growth rate in 1H, and in the case of the glove makers, both ASP and volumes may see a decline. 

<p style="text-align: justify;">CureVac shares have been under selling pressure and fell ~20% in September. For the same period shares of key rivals Moderna and BioNTech rose 7% and ~9% respectively. Moderna and Johnson &amp; Johnson began Phase 3 clinical trials of COVID-19 vaccine candidates this month. The global race for coronavirus vaccine is entering the final stage and leaders are Moderna, Pfizer/BioNTech, AstraZeneca and Johnson &amp; Johnson. All these companies have already initiated larger scale clinical trials (phase 3) for a COVID-19 vaccine. However, management of CureVac is confident larger phase 2/3 study will be launched till the end of the year. </p><p style="text-align: justify;">In our insight we will focus on approaches, used by biotech companies to develop coronavirus vaccines, and find out how CureVac positions itself as one of the leaders with the fast and disruptive mRNA technology.</p>

CureVac shares have been under selling pressure and fell ~20% in September. For the same period shares of key rivals Moderna and BioNTech rose 7% and ~9% respectively. Moderna and Johnson &amp; Johnson began Phase 3 clinical trials of COVID-19 vaccine candidates this month. The global race for coronavirus vaccine is entering the final stage and leaders are Moderna, Pfizer/BioNTech, AstraZeneca and Johnson &amp; Johnson. All these companies have already initiated larger scale clinical trials (phase 3) for a COVID-19 vaccine. However, management of CureVac is confident larger phase 2/3 study will be launched till the end of the year. In our insight we will focus on approaches, used by biotech companies to develop coronavirus vaccines, and find out how CureVac positions itself as one of the leaders with the fast and disruptive mRNA technology.

Expecting First Results From Phase 1 Clinical Trials Of COVID-19 Vaccine In October

Germany

BioNTech SE provides biotechnological solutions. The Company develops various types of treatments for cancer patients' tumors. BioNTech serves customers worldwide.

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BioNTech (BNTX US)

CureVac Stock May Surge Another 20-30% Under New Bull-Case Scenario

We see further upside potential for CureVac shares as the probability of success is increasing for its vaccine candidate CVnCoV and key mRNA-based...

Andrei Zakharov

Japan Airlines Placement - Tricky Tricky, Needs to Correct

Japan Airlines (9201 JP) plans to raise around US$1.4bn in order to shore up its balance sheet and aid its longer term transformation.

Sumeet Singh

Success of Moderna’s COVID-19 Vaccine May Give a Boost to Stocks of Messenger RNA Companies

mRNA-based COVID-19 vaccine producers made a big step forward to defeat coronavirus and prevent future pandemics around the world

Andrei Zakharov

Pfizer Vaccine: Winners and Losers

Similar to China Outbreak Theme: Winners and Losers , this insight will discuss the potential winners and losers from the announcement of the vaccine.

Henry Soediarko

Expecting First Results From Phase 1 Clinical Trials Of COVID-19 Vaccine In October

CureVac shares have been under selling pressure and fell ~20% in September. For the same period shares of key rivals Moderna and BioNTech rose 7%...

Andrei Zakharov

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