United States

InVivo Therapeutics Holdings Corp., through its subsidiary, is a medical device company. The Company is focused on utilizing polymers as a platform technology to develop treatments to improve function in individuals paralyzed as a result of traumatic spinal cord injury.

Venus Concept Inc. designs and develops medical aesthetic equipment. The Company provides hair transplantation systems for follicular unit extraction and harvesting. Venus Concept serves physicians and patients worldwide.

Invacare Corporation manufactures and distributes health care products to the non-acute care market on a worldwide basis.  The Company distributes its products to home care, mass retail, and institutional customers.  Invacare provides items such as respiratory products, home care beds, diabetic supplies, nursing home furniture, and manual and powerized wheelchairs.

Sientra, Inc. manufactures and markets plastic surgery implantable devices. The Company focuses on developing plastic surgery and aesthetics medicine such as cosmetic and reconstructive surgical devices including breast implants, tissue expanders, body contouring implants, and other specialty products. Sientra serves customers throughout the United States.

ViewRay Inc. develops radiation therapy technology for the treatment of cancer. The Company offers radiation therapy systems that images and treats cancer patients simultaneously. ViewRay serves customers worldwide.

Viveve Medical, Inc. manufactures and distributes medical devices. The Company offers electromedical and electrotherapeutic apparatus for tissue restoration. Viveve Medical markets its products worldwide.

SmileDirectClub, LLC designs and manufactures dental equipment. The Company supplies invisible aligners and braces to  get straight teeth. SmileDirectClub serves customers in the United States.

Cutera, Inc. develops and manufactures aesthetic laser systems.  The Company markets the CoolGlide family of products for removal of unwanted hair and treatment of vascular lesions.  Cutera markets the systems to dermatologists, plastic surgeons, and other practitioners worldwide.

ElectroCore, Inc. operates as a bio-electronic medicine company. The Company researches and develops therapeutic technologies for the treatment of multiple conditions in neurology and rheumatology. ElectroCore serves customers worldwide.

VolitionRx Limited operates as an epigenetics company. The Company offers a platform to develop and market blood tests designed to diagnose and monitor a range of life-altering diseases, including certain cancers and diseases associated with NETosis such as sepsis and COVID-19. VolitionRx offers its services in the United Kingdom, United States, Singapore, and Belgium.

USCOM Limited manufactures and develops cardiac monitoring devices.  The Company's products include the USCOM Monitor which provides an alternative to existing invasive methods of cardiac output measurement techniques.

Visgeneer Inc. develops and produces biomedical products associated with human diseases (cancer, cardiovascular disease, diabetes and gout etc.) and skin aging.

Allegra Orthopaedics Ltd researches, develops and manufactures prosthetic implants and medical devices. The Company also supplies products, technology and advice to its customers.

Analytica Limited is a biotechnology company that is involved in the research, development, and manufacture of medical diagnostic kits and retractable medical devices. The Company's products are used for detection of ovarian cancer, gluten intolerance, and various antibodies.

Pixium Vision SA develops retinal implant systems. The Company develops epi-retinal and sub-retinal implant systems to treat patients who have lost their sight, with the intention of improving their vision and enabling them to lead more independent lives. Pixium Vision markets its systems throughout Europe.

TruScreen Group Limited develops medical technology. The Company develops cervical cancer screening system comprising a medical device and process designed to detect the presence of pre-cancerous and cancerous tissue on the cervix in real time. TruScreen Group serves customers worldwide.

Immunovia AB manufactures health care devices. The Company offers bioinformatic devices that helps in the diagnosis of cancer, predicting disease progression, and monitoring the therapeutic responsiveness of cancers. Immunovia serves clients in Sweden.

Allium Medical Solutions Ltd develops and produces medical equipment. The Company manufactures and markets minimally invasive products. Allium Medical Solutions serves customers worldwide.

Imagion Biosystems Limited manufactures and supplies medical equipment. The Company offers a bio-imaging detection technology that uses disease specific targeting nanoparticles and highly sensitive detectors to locate tumors and other diseased cells by their molecular signature. Imagion Biosystems serves the healthcare sector worldwide.

Visioneering Technologies, Inc. (VTI) provides ophthalmic devices. The Company offers contact and intraocular lenses, as well as focuses on in-eye and on-eye solutions for the correction of presbyopia and myopia progression control. VTI serves customers in the United States.

Aethlon Medical, Inc. operates as a medical device company. The Company provides a platform to develop medical devices that target the selective removal of disease-promoting particles from the circulatory system. Aethlon Medical develops medical devices that address unmet medical needs in cancer, infectious disease, and other life-threatening conditions.

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