In today’s briefing:
- CHA Biotech Announces A Capital Raise of 41% of Outstanding Shares
- MIRA: IND Application Submitted to FDA
- MTVA: Compelling Data for DA-1241 in Phase 2a MASH Trial
CHA Biotech Announces A Capital Raise of 41% of Outstanding Shares
- On 20 December, Chabiotech (085660 KS) announced that it plans to conduct a rights offering capital raise of 250 billion won.
- The expected rights offering price is 10,800 won (27.3% lower than current price of 14,860 won). A total of 23.148 million new shares (41% of outstanding shares) will be issued.
- This capital raise by CHA Biotech is likely to further negatively impact the company’s share price in the next several weeks as many investors are concerned about excessive shares dilution.
MIRA: IND Application Submitted to FDA
- MIRA Pharmaceuticals(MIRA) Company Sponsored Research Report
MTVA: Compelling Data for DA-1241 in Phase 2a MASH Trial
- On December 18, 2024, MetaVia announced positive topline results from the Phase 2a clinical trial of DA-1241 in patients with presumed metabolic dysfunction-associated steatohepatitis (MASH).
- The results showed a statistically significant decrease in alanine aminotransferase (ALT) levels, the trials primary outcome, for DA-1241 100 mg at weeks 4 and 8 and statistically significant results were also seen in controlled attenuation parameter (CAP) and hemoglobin A1c.
- DA-1241 was well tolerated with only 35% of patients on the 100 mg dose reporting a treatment related adverse event (TEAE) compared to 28% on placebo.