Daily BriefsHealthcare

Daily Brief Health Care: Beijing Strong Biotechnolo-A, Shenzhen New Industries Biomedical Engineering-A, China Traditional Chinese Medicine, Shanghai Fosun Pharmaceutical (Group), Zai Lab , Divi’s Laboratories, Akeso Biopharma Inc, Medtronic Plc and more

In today’s briefing:

  • CSI Medical Service Index Rebalance: Adds Could Outperform Deletes in the Coming Week
  • Quiddity CSI 300/​​500 Jun 24 Rebalance: 92% Hit Rate; US$3.7 One-Way Flows
  • Merger Arb Mondays (03 Jun) – China TCM, Huafa, GA Pack, SciClone, CF Logistics, Great Eastern
  • Fosun Pharma (2196 HK/600196.CH) To Privatize Henlius (2696.HK) – Things Are Not as Good as Expected
  • China Healthcare Weekly (Jun.2) – Innovent’s Trouble, Hengrui’s “smart Deal”, Zai Lab’s Pain Point
  • Divi’s Laboratories (DIVI IN): Custom Synthesis Business to Drive Future Growth
  • [Akeso (9926 HK, BUY, TP HK$58) Company Update]: AK112’s Win Unleashes Change in PD-1/L1 Landscape
  • Medtronic plc: Expansion Of Global Operations & Supply Chain Transformation! – Major Drivers


CSI Medical Service Index Rebalance: Adds Could Outperform Deletes in the Coming Week

By Brian Freitas

  • CSI announced the changes for the June rebalance after market close on 31 May and the changes will be effective after the close of trading on 14 June.
  • There are 5 adds/deletes – we correctly forecasted 3 adds and all 5 deletes. Passives need to trade 0.5-3x ADV on the adds and 0.5-2.1x ADV on the deletes.
  • With the index not very widely forecasted, the adds could outperform the deletes over the next week in a repeat of the performance at the December rebalance.

Quiddity CSI 300/​​500 Jun 24 Rebalance: 92% Hit Rate; US$3.7 One-Way Flows

By Janaghan Jeyakumar, CFA

  • The June 2024 index review results for China’s CSI 300 and CSI 500 indices were announced after market close on Friday 31st May 2024.
  • There will be 12 changes in CSI 300 and 50 changes in CSI 500 which could collectively cause one-way index flows of ~US$3.7bn during the June 2024 index rebal event.
  • Compared to Quiddity’s final expectations, 114 out of the 124 index changes (both ways) were correct translating to a hit rate of 92%. 


Fosun Pharma (2196 HK/600196.CH) To Privatize Henlius (2696.HK) – Things Are Not as Good as Expected

By Xinyao (Criss) Wang

  • It is said that Fosun Pharma plans to privatize Henlius. There’re doubts about how to solve the debt problem/cash flow pressure of Fosun Pharma. A third party could be involved.
  • Shareholders may not be willing to accept an Offer Price that is significantly below IPO price. It’s also possible that shareholders vote against the privatization. So, there are many uncertainties.
  • Deal talks are still ongoing. It’s difficult to see clearly what’s happening under the table. Valuation logic of Fosun Pharma should be more like PE/VC firms not traditional pharmaceutical company.

China Healthcare Weekly (Jun.2) – Innovent’s Trouble, Hengrui’s “smart Deal”, Zai Lab’s Pain Point

By Xinyao (Criss) Wang

  • Innovent’s 24Q1 product sales was up just 6% QoQ. The overall data shows that PD-1 growth has entered a bottleneck. This makes 24H2 YoY growth rate uncertain.
  • The deal between Hengrui and Hercules is different from traditional license-out cooperation, but belong to asset spin-off in essence, which is a “smart deal” and also a meaningful attempt.
  • There’re some positive signals in Zai Lab’s 24Q1 performance, but the pain points of business model severely limit its profitability/revenue scale. Zai Lab still has a long way to go.

Divi’s Laboratories (DIVI IN): Custom Synthesis Business to Drive Future Growth

By Tina Banerjee

  • Divi’s Laboratories (DIVI IN) reported steady performance in Q4FY24, marked by YoY and sequential growth in revenue and improvement in profitability. Double-digit growth is expected to continue.
  • Custom Synthesis business grew 47% YoY and 38% QoQ to INR12B in Q4FY24, driven by increasing value realization from existing commercial projects and addition of new projects to the portfolio.
  • In Custom Synthesis, Divi’s Lab is in the process of entering into a long-term supply agreement with an MNC customer and is planning for capacity addition at its manufacturing facility.

[Akeso (9926 HK, BUY, TP HK$58) Company Update]: AK112’s Win Unleashes Change in PD-1/L1 Landscape

By Eric Wen

  • Ivonescimab’s (AK112) head-to-head clinical win against Keytruda (Pembrolizumab) reaffirmed Akeso’s standing as the flag-bearer of Chinese innovative drugs. It also affirmed its business model of specialized R&D+flexible distribution. 
  • This success might be followed by a similar win globally in 2025-27,as well as AK112 and 104’s head-to-head win against Tislelizumab.
  • We reiterate our BUY rating on Akeso and adjust TP to HK$58 to reflect revenue share from AK112 to come in from 2025 but in bulk after 2027

Medtronic plc: Expansion Of Global Operations & Supply Chain Transformation! – Major Drivers

By Baptista Research

  • In its fiscal year 2024 Q4 earnings, Medtronic reported significant revenue growth and strong earnings, demonstrating the effectiveness of its strategies to drive growth and profitability.
  • The company’s four segments delivered mid-single-digit or higher revenue growth, with total revenue growth exceeding 5% for the full fiscal year.
  • This record growth was largely driven by new product innovations across Medtronic’s cardiovascular, robotics, diabetes care, and other therapeutic segments.

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